Ointments are viscous semisolid preparations for external application to the skin or mucous membranes. They are usually medicated and can be applied in order to heal, soothe or protect. For topical dermatological products, drugs are delivered into the skin for treatment of dermal disorder. For transdermal products, drugs are delivered through the skin to the general circulation.
There are two types of ointments, medicated and non-medicated. Non-medicated ointments are sometimes referred to as ointment bases. Apart from their protectant, emollient, or lubricating effect, they are commonly used as vehicles in medicated ointments.
To incorporate solid into the ointment base, an ointment mill is often used to ensure that the final product will not be gritty. The particle size of a powder or crystalline material is usually reduced before incorporation. If preparing a large quantity of ointment, here are the 2 simple steps that can greatly increase your output and produce smooth and elegant ointments.
1) Mix together the solid and the ointment base with electric mortar & pestle.
2) Put the mixture through a three roll mill 1 to 2 passes.